May 10, 2023
Chris graduates with PhD: Chris defended his thesis and graduated with PhD degree from Binghamton University. Congrats Chris!

May 8, 2023
Paper published: Chris, Motiar and Vipin published a paper Triplex-Forming Peptide Nucleic Acid Controls Dynamic Conformations of RNA Bulges in Journal of the American Chemical Society. Congrats Michael, Julien, Venu, Praveen, Lamorna and Chandan!
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March 22, 2023
Chris receives Graduate Student Excellence Award: Chris received the 2023 Binghamton University Graduate Student Award for Excellence in Research. Congrats Chris!

March 9, 2023
Invited Lecture: Eriks delivered an invited talk "Amide-Modified Oligonucleotides for Chemical Control of Functional RNAs" at Eli Lilly and Company

December 29, 2022
Paper published: Michael, Julien, Venu, Praveen, Lamorna and Chandan published a paper Amide Modifications in the Seed Region of the Guide Strand Improve the On-Target Specificity of Short Interfering RNA in ACS Chemical Biology. Congrats Michael, Julien, Venu, Praveen, Lamorna and Chandan!
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May 31, 2022
Paper published: Chris, in collaboration with colleagues from Latvian Institute of Organic Synthesis, published a paper Extended 2-Guanidyl Pyridine PNA Nucleobase for Triple-Helical Hoogsteen Recognition of Cytosine in Double Stranded RNA in Chemical Communications. Congrats Chris!
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May 31, 2022
Paper published: Julien and Chandan published a paper Optimization of Automated Synthesis of Amide-Linked RNA in ACS Omega. Congrats Julien and Chandan!
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February 28, 2022
Paper published: Venu, Praveen and Lamorna published a paper Amide Internucleoside Linkages Are Well Tolerated in Protospacer Adjacent Motif-Distal Region of CRISPR RNAs in ACS Chemical Biology. Congrats Venu, Praveen and Lamorna!
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December 16, 2021
Paper published: Nikita and Ilze published a paper Cellular uptake of 2-aminopyridine-modified peptide nucleic acids conjugated with cell-penetrating peptides in Biopolymers. Congrats Nikita and Ilze!
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November 1, 2021
New Project funded! Our group has received an R21 award from NIAID "Targeting SARS-CoV-2 RNA Pseudoknots Using Triplex-Forming Peptide Nucleic Acids".
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August 25, 2021
Eriks receives ACS Award: Eriks received the 2021 Melville L. Wolfrom Award from the Division of Carbohydrate Chemistry at the American Chemical Society National Meeting in Atlanta. The Award recognizes individuals who have provided outstanding service to the Division of Carbohydrate Chemistry and the field of carbohydrate chemistry.

June 11, 2021
Paper published: Nikita and Diana, in collaboration with colleagues from FIBER, Konan University in Japan, published a paper Triple-Helical Binding of Peptide Nucleic Acid Inhibits Maturation of Endogenous MicroRNA-197 in ACS Chemical Biology. Congrats Nikita and Diana!
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June 7, 2021
Paper published: Chris, Nikita and Justin published a paper The 2-Aminopyridine Nucleobase Improves Triple-Helical Recognition of RNA and DNA When Used Instead of Pseudoisocytosine in Peptide Nucleic Acids in Biochemistry. Congrats Chris, Nikita and Justin!
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May 13, 2021
PhD Graduation: Congratulations Nikita and Julien on receiving PhD degrees! Best of luck in your future endeavors!

April 21, 2021
Paper published: Nikita and Justin, in collaboration with colleagues from Latvian Institute of Organic Synthesis, published a paper Pyridazine Nucleobase in Triplex-Forming PNA Improves Recognition of Cytosine Interruptions of Polypurine Tracts in RNA in ACS Chemical Biology. Congrats Nikita and Justin!
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January 13, 2021
Paper published: Nikita, in collaboration with colleagues from Elizabethtown College and Latvian Institute of Organic Synthesis, published a paper Extended Peptide Nucleic Acid Nucleobases Based on Isoorotic Acid for the Recognition of A–U Base Pairs in Double-Stranded RNA in Chemistry - A European Journal. Congrats Nikita!
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October 28, 2020
Paper published: Chris published a paper Impact of Chirality and Position of Lysine Conjugation in Triplex-Forming Peptide Nucleic Acids in ACS Omega. Congrats Chris!
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August 10, 2020
Eriks wins ACS Award: Eriks has been selected to receive the 2021 Melville L. Wolfrom Award from the Division of Carbohydrate Chemistry, American Chemical Society. The Award recognizes individuals who have provided outstanding service to the Division of Carbohydrate Chemistry and the field of carbohydrate chemistry.

July 22, 2020
Paper published: Vipin and Nikita published a paper Triplex‐Forming Peptide Nucleic Acids with Extended Backbones in ChemBioChem. Congrats Vipin and Nikita!
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July 13, 2020
Paper published: Venu and Eriks published a paper Amide-Modified RNA: Using Protein Backbone to Modulate Function of Short Interfering RNAs in Accounts of Chemical Research. Their Account was featured as a Cover Picture of the September issue of the Journal.
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November 20, 2019
Paper published: Venu and Julien published a paper Synthesis and Biological Activity of Short Interfering RNAs Having Several Consecutive Amide Internucleoside Linkages in Chemistry - A European Journal. Congrats Venu and Julien!
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October 14, 2019
Eriks delivered an invited talk Sequence Selective Recognition of Double-Stranded RNA by Cationic Nucleobase and Backbone-Modified Peptide Nucleic Acids at the 15th Annual Meeting of the Oligonucleotide Therapeutics Society in Munich, Germany.

September 20, 2019
Paper published: Nikita, in collaboration with colleagues from Latvian Institute of Organic Synthesis, Elizabethtown College and University of Rochester, published a paper Synthesis and RNA-Binding Properties of Extended Nucleobases for Triplex-Forming Peptide Nucleic Acids in Journal of Organic Chemistry. Congrats Nikita!
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June 23-27, 2019
The group attended Nucleosides, Nucleotides and Oligonucleotides Gordon Research Conference at Salve Regina University, Newport RI. Venu, Julien, Nikita and Chris presented posters. Eriks delivered an invited talk Amide-Modified RNA: Synthesis, Structure And RNA Interference Activity

February 11, 2019
Paper published: Venu in collaboration with colleagues from University of Rochester and Elizabethtown College, published a paper Synthetic, Structural, and RNA Binding Studies on 2‐Aminopyridine‐Modified Triplex‐Forming Peptide Nucleic Acids in Chemistry - A European Journal. Congrats Venu!
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February 1, 2019
Our group has received a Maximizing Investigators' Research Award (MIRA R35 GM130207, $2,040,290 for 5 years) from the National Institute of General Medical Sciences (NIGMS) to support our entire research portfolio on Chemical Approaches to Control the Function of Regulatory RNAs.

August 27-30, 2018
Congratulations Venu on the 1st Place Poster Award in the Postdoc Category at the XXIII International Roundtable on Nucleosides, Nucleotides & Nucleic Acids UC San Diego, La Jolla, California. Julien and Nikita also presented posters at this meeting.

January 3, 2018
Paper published: Irina, Venu, Daniel and Samwel in collaboration with Dharmacon, Vandebilt and Rochester researchers have published a paper A Single Amide Linkage in the Passenger Strand Suppresses Its Activity and Enhances Guide Strand Targeting of siRNAs in ACS Chemical Biology. Congrats Irina, Venu, Daniel and Samwel!
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September 27, 2017
Paper published: In collaboration with Scott Kennedy (University of Rochester) Irina has published a paper 2-Methoxypyridine as a Thymidine Mimic in Watson--Crick Base Pairs of DNA and PNA: Synthesis, Thermal Stability, and NMR Structural Studies in ChemBioChem. Congrats Irina!
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August 21, 2017
Paper published: Daniel and Samwel in collaboration with Dharmacon, Vandebilt and Rochester researchers have published a paper Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs in Nucleic Acids Research. Congrats Daniel and Samwel!
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August 1, 2017
NSF grant application funded: Our group has been awarded a grant totaling $502K from the National Science Foundation to work on a collaborative research project: Nucleobase-Modified Peptide Nucleic Acid (PNA) for Sequence Selective Triple-Helical Recognition of Non-Coding Ribonucleic Acid (RNA). The project is a partnership with Dr. James A. MacKay who received a complementary award totaling $196K from the National Science Foundation to support related activities with undergraduates at Elizabethtown College.
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July 21, 2017
Paper published: Venu has published a paper Concurrent Hydrogenation of Three Functional Groups Enables Synthesis of C3'-Homologated Nucleoside Amino Acids in Organic Letters. Congrats Venu!
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May 19, 2017
Congratulations Diana and Samwel on successful defense of PhD thesis and graduation!

December 17, 2016
Paper published: In collaboration with Dennis McGee (Biology) Diana and Yannis have published a paper Sequence-selective recognition of double-stranded RNA and enhanced cellular uptake of cationic nucleobase and backbone-modified peptide nucleic acids in RNA journal. Congrats Diana and Yannis!
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