February 10, 2025
Paper published: Brandon published a paper 2-Aminopyridine Nucleobases Enable DNA Invasion by Peptide Nucleic Acid Clamps at Physiological Conditions in Chemical Communications. Congrats Brandon!
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January 29, 2025
Invited Lecture: Eriks delivered an invited talk "Amide-Modified RNA: Using Protein Backbone to Improve Specificity of siRNAs" at the 6th RNAi-Based Therapeutics Summit in Boston

January 15, 2025
Paper published: Chandan, Michael and Jayamini published a paper Amide Internucleoside Linkages Suppress the MicroRNA-like Off-Target Activity of Short Interfering RNA in ACS Chemical Biology. Congrats Chandan, Michael and Jayamini!
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December 22, 2024
Paper published: Sara in collaboration with colleagues from Latvian Institute of Organic Synthesis published a paper Recognition of Noncanonical RNA Base Pairs Using Triplex-Forming Peptide Nucleic Acids in ACS Chemical Biology. Congrats Sara, Vladislavs and Martins!
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October 4, 2024
Invited Lecture: Eriks delivered an invited talk "Amide-Modified RNA: Using Protein Backbone to Modulate Function of RNA" at Michigan Technological University

September 7, 2024
Invited Lecture: Eriks delivered an invited talk "Sequence Selective Recognition of Double-Stranded RNA by Nucleobase-Modified Peptide Nucleic Acids" at The International Nucleic Acid Science Symposium, Post-Symposium of IRT2024, Nihon University, Tokyo

September 6, 2024
Ilze received Chu Family Scholarship: Ilze presented a poster and received the prestigious Chu Family Scholarship at the XXV International Round Table on Nucleosides, Nucleotides and Nucleic Acids in Tokyo. Congrats Ilze!

August 1, 2024
New Project funded! Our group has renewed the NSF award “Collaborative Research: Nucleobase-Modified PNA for Sequence Selective Triple-Helical Recognition of Non-Coding RNA” (CHE – 2427911/2427912) to support our collaboration with Professor James MacKay at Elizabethtown College.

June 29, 2024
Paper published: Motiar, Chris and Brandon published a paper Peptide Nucleic Acids (PNAs) Control Function of SARS-CoV-2 Frameshifting Stimulatory Element Trough PNA-RNA-PNA Triplex Formation in Heliyon. Congrats Motiar, Chris and Brandon!
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May 8, 2024
Ilze receives Fellowship: Ilze receives Provost Dissertation Fellowship. Congrats Ilze!

March 20, 2024
Invited Lecture: Eriks delivered an invited talk "Amide-Modified Oligonucleotides for Chemical Control of Functional RNAs" at Oligonucleotide & Peptide Therapeutics Conference (TIDES Asia), Kyoto, Japan

March 11, 2024
Invited Lecture: Eriks delivered an invited talk "Sequence Selective Recognition of Double-Stranded RNA by Cationic Nucleobase and Backbone-Modified Peptide Nucleic Acids" at Nihon University, Tokyo, Japan

February 29, 2024
Invited Lecture: Eriks delivered an invited talk "Amide-Modified RNA: Using Protein Backbone to Modulate Function of RNA" at Special FIBER International Summit for Nucleic Acids (S-FISNA), Konan University, Kobe, Japan

February 5, 2024
Paper published: Chandan and Michael published a paper Synthesis and Properties of RNA Modified with Cationic Amine Internucleoside Linkage in ACS Chemical Biology. Congrats Chandan and Michael!
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February 3, 2024
Paper published: Ilze and Mohammed published an invited paper Comparison of 2-Aminopyridine and 4-Thiopseudisocytosine PNA Nucleobases for Hoogsteen Recognition of Guanosine in RNA in ACS Omega. Congrats Ilze and Mohammed!
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January 22, 2024
New Project funded! Our group has renewed the Maximizing Investigators' Research Award (MIRA R35 GM130207, $2,109,000 for 5 years) from the National Institute of General Medical Sciences (NIGMS) to support our entire research portfolio on Chemical Approaches to Control the Function of Regulatory RNAs.

January 12, 2024
Paper published: Martins (Latvian Institute of Organic Synthesis), James (Elizabethtown College) and Eriks published a Feature Article Triplex-forming peptide nucleic acids as emerging ligands to modulate structure and function of complex RNAs in Chemical Communications.
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November 17, 2023
Paper published: Our group in collaboration with colleagues from Elizabethtown College and Latvian Institute of Organic Synthesis, published an invited paper Synthesis of 2-Aminopyridine-Modified Peptide Nucleic Acids in Synlett. Congrats Ilze, Brandon, Sara, and Chris!
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October 19, 2023
Invited Lecture: Eriks delivered an invited talk "Amide-Modified Oligonucleotides for Chemical Control of Functional RNAs" at Advances in Noncanonical Nucleic Acids, (ANNA 2023) Maribor, Slovenia

August 30, 2023
Paper published: Brandon, in collaboration with colleagues from Elizabethtown College and Latvian Institute of Organic Synthesis, published a paper Improved Triplex-Forming Isoorotamide PNA Nucleobases for A-U Recognition of RNA Duplexes in Chemistry – A European Journal. Congrats Brandon!
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July 24, 2023
Invited Lecture: Eriks delivered an invited talk "Sequence Selective Recognition of Double-Stranded RNA by Cationic Nucleobase and Backbone-Modified Peptide Nucleic Acids" at Tohoku University, Sendai, Japan

June 25-30, 2023
Conference particiation: Ilze, Michael, Sara, Brandon, Jayamini, and Motiar presented posters at the Nucleosides, Nucleotides and Oligonucleotides Gordon Research Conference in Newport. Sara and Brandon won the Best Poster Awards. Congrats Sara and Brandon!

June 15, 2023
Paper published: Ilze, in collaboration with colleagues from Latvian Institute of Organic Synthesis, published a paper Nucleobase and Linker Modification for Triple-Helical Recognition of Pyrimidines in RNA Using Peptide Nucleic Acids in ChemBioChem. Congrats Ilze!
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May 10, 2023
Chris graduates with PhD: Chris defended his thesis and graduated with PhD degree from Binghamton University. Congrats Chris!

May 8, 2023
Paper published: Chris, Motiar and Vipin published a paper Triplex-Forming Peptide Nucleic Acid Controls Dynamic Conformations of RNA Bulges in Journal of the American Chemical Society. Congrats Chris, Motiar and Vipin!
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March 22, 2023
Chris receives Graduate Student Excellence Award: Chris received the 2023 Binghamton University Graduate Student Award for Excellence in Research. Congrats Chris!

March 9, 2023
Invited Lecture: Eriks delivered an invited talk "Amide-Modified Oligonucleotides for Chemical Control of Functional RNAs" at Eli Lilly and Company

December 29, 2022
Paper published: Michael, Julien, Venu, Praveen, Lamorna and Chandan published a paper Amide Modifications in the Seed Region of the Guide Strand Improve the On-Target Specificity of Short Interfering RNA in ACS Chemical Biology. Congrats Michael, Julien, Venu, Praveen, Lamorna and Chandan!
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May 31, 2022
Paper published: Chris, in collaboration with colleagues from Latvian Institute of Organic Synthesis, published a paper Extended 2-Guanidyl Pyridine PNA Nucleobase for Triple-Helical Hoogsteen Recognition of Cytosine in Double Stranded RNA in Chemical Communications. Congrats Chris!
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May 31, 2022
Paper published: Julien and Chandan published a paper Optimization of Automated Synthesis of Amide-Linked RNA in ACS Omega. Congrats Julien and Chandan!
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February 28, 2022
Paper published: Venu, Praveen and Lamorna published a paper Amide Internucleoside Linkages Are Well Tolerated in Protospacer Adjacent Motif-Distal Region of CRISPR RNAs in ACS Chemical Biology. Congrats Venu, Praveen and Lamorna!
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December 16, 2021
Paper published: Nikita and Ilze published a paper Cellular uptake of 2-aminopyridine-modified peptide nucleic acids conjugated with cell-penetrating peptides in Biopolymers. Congrats Nikita and Ilze!
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November 1, 2021
New Project funded! Our group has received an R21 award from NIAID "Targeting SARS-CoV-2 RNA Pseudoknots Using Triplex-Forming Peptide Nucleic Acids".
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August 25, 2021
Eriks receives ACS Award: Eriks received the 2021 Melville L. Wolfrom Award from the Division of Carbohydrate Chemistry at the American Chemical Society National Meeting in Atlanta. The Award recognizes individuals who have provided outstanding service to the Division of Carbohydrate Chemistry and the field of carbohydrate chemistry.

June 11, 2021
Paper published: Nikita and Diana, in collaboration with colleagues from FIBER, Konan University in Japan, published a paper Triple-Helical Binding of Peptide Nucleic Acid Inhibits Maturation of Endogenous MicroRNA-197 in ACS Chemical Biology. Congrats Nikita and Diana!
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June 7, 2021
Paper published: Chris, Nikita and Justin published a paper The 2-Aminopyridine Nucleobase Improves Triple-Helical Recognition of RNA and DNA When Used Instead of Pseudoisocytosine in Peptide Nucleic Acids in Biochemistry. Congrats Chris, Nikita and Justin!
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May 13, 2021
PhD Graduation: Congratulations Nikita and Julien on receiving PhD degrees! Best of luck in your future endeavors!

April 21, 2021
Paper published: Nikita and Justin, in collaboration with colleagues from Latvian Institute of Organic Synthesis, published a paper Pyridazine Nucleobase in Triplex-Forming PNA Improves Recognition of Cytosine Interruptions of Polypurine Tracts in RNA in ACS Chemical Biology. Congrats Nikita and Justin!
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January 13, 2021
Paper published: Nikita, in collaboration with colleagues from Elizabethtown College and Latvian Institute of Organic Synthesis, published a paper Extended Peptide Nucleic Acid Nucleobases Based on Isoorotic Acid for the Recognition of A–U Base Pairs in Double-Stranded RNA in Chemistry - A European Journal. Congrats Nikita!
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